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KMID : 0605620130200020029
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Journal of Korean Society of Biological Psychiatry
2013 Volume.20 No. 2 p.29 ~ p.30
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Ketamine as a Rapid-Acting Antidepressant.
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Oh Dae-Young
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Abstract
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First-line therapy of depression is a pharmacological treatment. Many prescribed antidepressants modulate monoamine neurotransmitters including serotonin, norepinephrine and dopamine. Recently, Ketamine, an N-methyl-D-aspartate receptor antagonist, has received attention and has been investigated for clinical trials and neurobiological studies. Here, I introduce ketamine as a rapid-acting antidepressant.
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KEYWORD
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Depression, NMDA, Ketamine, mTOR
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